Homozygous and heterozygous p53 knockout rats develop metastasizing sarcomas with high frequency

Keyphrases

• Metastasizing 100%
• Sarcoma 100%
• Knockout Rat 100%
• Tumor Protein p53 (TP53) 66%
• Tumorigenesis 66%
• Tumor 33%
• Homozygosity 33%
• Mutagenesis 33%
• Tumor Suppressor Gene 33%
• Tumor Suppressor 33%
• Human Cancer 33%
• Mutant p53 33%
• Loss of Heterozygosity 33%
• Knock-in Mouse Model 33%
• Rodents 33%
• Molecular Analysis 33%
• Early Onset 33%
• Pulmonary Metastasis 33%
• Gatekeepers 33%
• Genotoxic Studies 33%
• Homozygous mutant 33%
• Mutant Rat 33%

Biochemistry, Genetics and Molecular Biology

• P53 100%
• Knockout Rat 100%
• Allele 60%
• Carcinogenesis 40%
• Animal Model 20%
• Mutagenesis 20%
• Tumor Suppressor Gene 20%
• Tumor Suppressor Protein 20%
• Wild Type 20%
• Loss of Heterozygosity 20%
• Homozygosity 20%
• Knockout Model 20%
• Rat Mutant 20%