HORMA domains at the heart of meiotic chromosome dynamics

Gerben Vader; Andrea Musacchio

doi:10.1016/j.devcel.2014.11.009

HORMA domains at the heart of meiotic chromosome dynamics

Gerben Vader, Andrea Musacchio

Onderzoeksoutput: Bijdrage aan tijdschrift › Artikel › peer review

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HORMA domain proteins are required for the careful orchestration of chromosomal organization during meiosis. Kim et al. (2014) and Silva et al. (2014) now provide structural and functional insights into the roles of C. elegans HORMA proteins, revealing parallels to the function of the HORMA protein MAD2 in mitotic checkpoint signaling.

Originele taal-2	Engels
Pagina's (van-tot)	389-91
Aantal pagina's	3
Tijdschrift	Developmental Cell
Volume	31
Nummer van het tijdschrift	4
DOI's	https://doi.org/10.1016/j.devcel.2014.11.009
Status	Gepubliceerd - 24 nov. 2014
Extern gepubliceerd	Ja

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10.1016/j.devcel.2014.11.009

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title = "HORMA domains at the heart of meiotic chromosome dynamics",

abstract = "HORMA domain proteins are required for the careful orchestration of chromosomal organization during meiosis. Kim et al. (2014) and Silva et al. (2014) now provide structural and functional insights into the roles of C. elegans HORMA proteins, revealing parallels to the function of the HORMA protein MAD2 in mitotic checkpoint signaling.",

keywords = "Animals, Caenorhabditis elegans/metabolism, Caenorhabditis elegans Proteins/metabolism, Cell Cycle Proteins/metabolism, Chromosome Pairing/genetics, Chromosomes/metabolism, Meiosis/physiology, Signal Transduction/physiology, Synaptonemal Complex/metabolism",

author = "Gerben Vader and Andrea Musacchio",

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KW - Animals

KW - Caenorhabditis elegans/metabolism

KW - Caenorhabditis elegans Proteins/metabolism

KW - Cell Cycle Proteins/metabolism

KW - Chromosome Pairing/genetics

KW - Chromosomes/metabolism

KW - Meiosis/physiology

KW - Signal Transduction/physiology

KW - Synaptonemal Complex/metabolism

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HORMA domains at the heart of meiotic chromosome dynamics

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