Hypereosinophilic syndrome in children

M. Van Grotel, M. de Hoog, R. R. de Krijger, H. B. Beverloo, M. M. van den Heuvel-Eibrink

Onderzoeksoutput: Bijdrage aan tijdschriftArtikelpeer review

24 Citaten (Scopus)


Recently, according to the Hypereosinophilic Diseases Working Group of the International Eosinophil Society, six variants of hypereosinophilic syndrome have been proposed, i.e. (1) myeloproliferative, (2) lymphoproliferative, (3) idiopathic/undefined, (4) overlapping, (5) associated and (6) familial variant. Hypereosinophilic syndrome is a rare disorder in children and can occur at any age during childhood. Corticosteroids are the treatment of choice, whereas other treatment options are hydroxyurea, IFNα, imatinib, vincristine, mepolizumab. We present a fulminant fatal case of hypereosinophilic syndrome in a teenager with an initial presentation of an idiopathic thrombocytopenia (ITP) and present a narrative review of literature.

Originele taal-2Engels
Pagina's (van-tot)1249-1254
Aantal pagina's6
TijdschriftLeukemia Research
Nummer van het tijdschrift10
StatusGepubliceerd - okt. 2012
Extern gepubliceerdJa


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