Keyphrases
Acute Lymphoblastic Leukemia
27%
AKT Pathway
9%
ALL Subtypes
9%
ALL Treatment
9%
Anti-apoptotic
9%
Bcl-xL
9%
Cancer Causes
9%
Cancer Mortality
9%
Cellular Mechanisms
9%
Childhood Cancer
9%
Clinical Outcomes
18%
Clinical Significance
9%
Cohort Size
9%
Copy number
9%
Data Combination
9%
Downstream Targets
9%
Drug Response
9%
Early Thymic Progenitors
9%
Expression Construct
9%
Functional Studies
9%
Genetic Mechanism
9%
Genome Sequencing
100%
Genomic Datasets
9%
Glycogen Synthase kinase-3β (GSK-3β)
9%
High-risk Disease
9%
IL-7 Receptor
100%
Induced Cell Death
18%
Interleukin-7 Receptor
90%
JAK3
27%
Janus Kinase 1 (JAK1)
36%
L-asparaginase
9%
Lentiviral Expression
9%
Low Incidence
9%
Mammalian Target of Rapamycin (mTOR)
27%
MEK-ERK
9%
MEK-ERK Pathway
9%
Mutated Genes
9%
Mutation Data
9%
Mutation Resistance
100%
Myeloid Cell leukemia-1 (Mcl-1)
9%
Pediatric
100%
Pediatric Acute Lymphoblastic Leukemia
18%
PI3K-mTOR Inhibitors
9%
Poor Outcome
27%
Prednisolone
9%
Primary T Cells
9%
Pro-apoptotic
9%
Prospective Clinical Study
9%
Receptor mutations
100%
Receptor Signaling
63%
Resistance to Treatment
9%
Sequence Method
9%
Sequencing Studies
100%
Signal Transduction Inhibitors
18%
Signaling Genes
9%
Signaling Molecules
18%
Signaling Pathway
18%
Specific mutation
9%
Specific T Cells
9%
Steroid Receptors
9%
Steroid Resistance
100%
Steroid Response
9%
Steroid Treatment
9%
Steroid-induced
18%
Steroid-sensitive
36%
Strongest Activations
9%
T-cell Acute Lymphoblastic Leukemia (T-ALL)
100%
T-cell ALL
100%
Targeted Sequencing
9%
Treatment-free Remission
9%
Treatment-seeking Sample
9%
Unbiased Sequencing
9%
Whole Genome Sequencing
9%
Medicine and Dentistry
Acute Lymphoblastic Leukemia
100%
Antiapoptotic
9%
Asparaginase
9%
Cell Death
18%
Cell Line
18%
Cellular Mechanism
9%
Childhood Cancer
9%
Clinical Study
9%
Diagnosis
9%
Disease
9%
Drug Response
9%
Exome Sequencing
9%
Genome Sequencing
100%
In Vitro
18%
Interleukin 7
100%
Interleukin 7 Receptor
90%
Malignant Neoplasm
9%
Mammalian Target of Rapamycin
27%
Mammalian Target of Rapamycin Inhibitor
9%
Pediatrics
100%
Prednisolone
9%
Receptor
100%
Signal Transduction
27%
Signaling Molecule
18%
Steroid Receptor
9%
Steroid Resistance
100%
Steroid Treatment
9%
T Cell
100%
Vincristine
9%
Whole Genome Sequencing
9%
Pharmacology, Toxicology and Pharmaceutical Science
Acute Lymphoblastic Leukemia
100%
Antiapoptotic
10%
Asparaginase
10%
Childhood Cancer
10%
Clinical Study
10%
Disease
10%
Interleukin 7
100%
Interleukin 7 Receptor
100%
Malignant Neoplasm
10%
Mammalian Target of Rapamycin Inhibitor
10%
Prednisolone
10%
Receptor
100%
Remission
10%
Steroid Receptor
10%
Steroid Resistance
100%
Steroid Treatment
10%
Vincristine
10%
Immunology and Microbiology
Cell Death
15%
Cell Line
15%
Drug Response
7%
Genome Sequencing
100%
Interleukin 7
100%
Interleukin-7 Receptor
76%
Prednisolone
7%
Signal Transduction
23%
T Cell
100%
Whole Exome Sequencing
7%
Whole Genome Sequencing
7%
Wild Type
23%
Biochemistry, Genetics and Molecular Biology
Interleukin-7 Receptor
76%
Prednisolone
7%