Imaged-guided focused ultrasound in combination with various formulations of doxorubicin for the treatment of diffuse intrinsic pontine glioma

Keyphrases

• Doxorubicin 100%
• Focused Ultrasound 100%
• Diffuse Intrinsic Pontine Glioma 100%
• Tumor 50%
• Blood-brain Barrier 37%
• Caelyx 37%
• Liposomal Formulation 37%
• Overall Survival 25%
• Xenograft Model 25%
• Bioluminescence Imaging 25%
• Ultrasound Treatment 25%
• Pontine 25%
• Tumor Cells 12%
• Effective Treatment 12%
• Xenograft 12%
• Microbubbles 12%
• Engraftment 12%
• No Significant Difference 12%
• Orthotopic Injection 12%
• Pontine Glioma 12%
• Healthy Controls 12%
• Treatment Effect 12%
• Treatment Group 12%
• Long Circulation 12%
• Nude 12%
• Drug Delivery System 12%
• Rapid Recovery 12%
• Preclinical Animal Models 12%
• Recovery Time 12%
• Non-invasive Method 12%
• Long-term Exposure 12%
• Liposomes 12%
• Survival Analysis 12%
• PEGylated 12%
• Single Treatment 12%
• Athymic 12%
• Tumor Response 12%
• Post Inoculation 12%
• Imaging Monitoring 12%

Immunology and Microbiology

• Xenograft 100%
• Blood Brain Barrier 100%
• Overall Survival 66%
• Bioluminescence 66%
• Tumor Cell 33%
• Engraftment 33%
• Microbubble 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Doxorubicin 100%
• Pontine Glioma 100%
• Neoplasm 45%
• Blood-Brain Barrier 27%
• Overall Survival 18%
• Side Effect 9%
• Antiinfective Agent 9%
• Liposome 9%
• Tumor Engraftment 9%
• Extravasation 9%