Integration of multiple lineage measurements from the same cell reconstructs parallel tumor evolution

Keyphrases

• Tumor Evolution 100%
• Multiple Lineages 100%
• Organoids 40%
• Patient-derived Organoids 40%
• Organoid Models 40%
• Colon Cancer 40%
• High-resolution 40%
• Viral Lineage 40%
• Chromosome 4 40%
• Chromosome 18 40%
• Aberrations 20%
• Clonal Evolution 20%
• Clinically Significant 20%
• Genetic Aberrations 20%
• Recurring 20%
• Colorectal Cancer 20%
• Tumor Heterogeneity 20%
• Barcoding 20%
• Lineage Tracing 20%
• Single-cell Sequencing Technology 20%
• Memorials 20%
• Tumor Clone 20%
• Event Order 20%
• Clone Size 20%
• Evolution Tree 20%
• Evolution Process 20%
• Chromosomal Aberrations 20%
• Evolution Experiment 20%
• Single-cell Whole-genome Sequencing 20%
• Colorectal Carcinoma 20%
• Evolutionary Model 20%
• Tumor Subpopulations 20%
• Parallel Evolution 20%

Biochemistry, Genetics and Molecular Biology

• Colon 100%
• Chromosome 18 100%
• Chromosome 4 100%
• Clonal Evolution 50%
• Whole Genome Sequencing 50%
• Phylogenetic Tree 50%
• Chromosomal Aberration 50%
• Genomics 50%

Immunology and Microbiology

• Organoid 100%
• Lineages 100%
• Colon 50%
• Chromosome 18 50%
• Chromosome 4 50%
• Colorectal Carcinoma 50%
• Clonal Evolution 25%
• Whole Genome Sequencing 25%
• Phylogenetic Tree 25%
• Single-Cell Sequencing 25%