TY - JOUR
T1 - Intravascular photoacoustic imaging of human coronary atherosclerosis
AU - Jansen, Krista
AU - Van Der Steen, Antonius F.W.
AU - Van Beusekom, Heleen M.M.
AU - Oosterhuis, J. Wolter
AU - Van Soest, Gijs
PY - 2011/3/1
Y1 - 2011/3/1
N2 - We demonstrate intravascular photoacoustic imaging of human coronary atherosclerotic plaque. The data was obtained from two fresh human coronary arteries ex vivo, showing different stages of disease. A 1:25mm diameter intravascular imaging catheter was built, comprising an angle-polished optical fiber adjacent to a 30 MHz ultrasound transducer. Specific photoacoustic imaging of lipid content, a key factor in vulnerable plaques that may lead to myocardial infarction, is achieved by spectroscopic imaging at different wavelengths between 1180 and 1230nm. Simultaneous imaging with intravascular ultrasound was performed. 2011 Optical Society of America.
AB - We demonstrate intravascular photoacoustic imaging of human coronary atherosclerotic plaque. The data was obtained from two fresh human coronary arteries ex vivo, showing different stages of disease. A 1:25mm diameter intravascular imaging catheter was built, comprising an angle-polished optical fiber adjacent to a 30 MHz ultrasound transducer. Specific photoacoustic imaging of lipid content, a key factor in vulnerable plaques that may lead to myocardial infarction, is achieved by spectroscopic imaging at different wavelengths between 1180 and 1230nm. Simultaneous imaging with intravascular ultrasound was performed. 2011 Optical Society of America.
UR - http://www.scopus.com/inward/record.url?scp=79952357487&partnerID=8YFLogxK
U2 - 10.1364/OL.36.000597
DO - 10.1364/OL.36.000597
M3 - Article
C2 - 21368919
AN - SCOPUS:79952357487
SN - 0146-9592
VL - 36
SP - 597
EP - 599
JO - Optics Letters
JF - Optics Letters
IS - 5
ER -