Invasive pulmonary aspergillosis associated with viral pneumonitis

Intan MW Dewi, Nico AF Janssen, Diletta Rosati, Mariolina Bruno, Mihai G. Netea, Roger JM Brüggemann, Paul E. Verweij, Frank L. van de Veerdonk

Onderzoeksoutput: Bijdrage aan tijdschriftArtikel recenserenpeer review

18 Citaten (Scopus)

Samenvatting

The occurrence of invasive pulmonary aspergillosis (IPA) in critically ill patients with viral pneumonitis has increasingly been reported in recent years. Influenza-associated pulmonary aspergillosis (IAPA) and COVID-19-associated pulmonary aspergillosis (CAPA) are the two most common forms of this fungal infection. These diseases cause high mortality in patients, most of whom were previously immunocompetent. The pathogenesis of IAPA and CAPA is still not fully understood, but involves viral, fungal and host factors. In this article, we discuss several aspects regarding IAPA and CAPA, including their possible pathogenesis, the use of immunotherapy, and future challenges.

Originele taal-2Engels
Pagina's (van-tot)21-27
Aantal pagina's7
TijdschriftCurrent Opinion in Microbiology
Volume62
DOI's
StatusGepubliceerd - aug. 2021
Extern gepubliceerdJa

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