TY - JOUR
T1 - Is restaging with chest and abdominal CT scan after neoadjuvant chemoradiotherapy for locally advanced rectal cancer necessary?
AU - Ayez, Ninos
AU - Alberda, Wijnand J.
AU - Burger, Jacobus W.A.
AU - Eggermont, Alexander M.M.
AU - Nuyttens, Joost J.M.E.
AU - Dwarkasing, Roy S.
AU - Willemssen, François E.J.A.
AU - Verhoef, Cornelis
PY - 2013/1
Y1 - 2013/1
N2 - Background: There is no evidence regarding restaging of patients with locally advanced rectal cancer after a long course of neoadjuvant radiotherapy with or without chemotherapy. This study evaluated the value of restaging with chest and abdominal computed tomographic (CT) scan after radiotherapy. Methods: Between January 2000 and December 2010, all newly diagnosed patients in our tertiary referral hospital, who underwent a long course of radiotherapy for locally advanced rectal cancer, were analyzed. Patients were only included if they had chest and abdominal imaging before and after radiotherapy treatment. Results: A total of 153 patients who met the inclusion criteria and were treated with curative intent were included. A change in treatment strategy due to new findings on the CT scan after radiotherapy was observed in 18 (12 %) of 153 patients. Twelve patients (8 %) were spared rectal surgery due to progressive metastatic disease. Conclusions: Restaging with a chest and abdominal CT scan after radiotherapy for locally advanced rectal cancer is advisable because additional findings may alter the treatment strategy.
AB - Background: There is no evidence regarding restaging of patients with locally advanced rectal cancer after a long course of neoadjuvant radiotherapy with or without chemotherapy. This study evaluated the value of restaging with chest and abdominal computed tomographic (CT) scan after radiotherapy. Methods: Between January 2000 and December 2010, all newly diagnosed patients in our tertiary referral hospital, who underwent a long course of radiotherapy for locally advanced rectal cancer, were analyzed. Patients were only included if they had chest and abdominal imaging before and after radiotherapy treatment. Results: A total of 153 patients who met the inclusion criteria and were treated with curative intent were included. A change in treatment strategy due to new findings on the CT scan after radiotherapy was observed in 18 (12 %) of 153 patients. Twelve patients (8 %) were spared rectal surgery due to progressive metastatic disease. Conclusions: Restaging with a chest and abdominal CT scan after radiotherapy for locally advanced rectal cancer is advisable because additional findings may alter the treatment strategy.
UR - http://www.scopus.com/inward/record.url?scp=84871789459&partnerID=8YFLogxK
U2 - 10.1245/s10434-012-2537-6
DO - 10.1245/s10434-012-2537-6
M3 - Article
C2 - 22875644
AN - SCOPUS:84871789459
SN - 1068-9265
VL - 20
SP - 155
EP - 160
JO - Annals of Surgical Oncology
JF - Annals of Surgical Oncology
IS - 1
ER -