TY - JOUR
T1 - Isolated limb perfusion of an irradiated foot with tumor necrosis factor, interferon, and melphalan
AU - Van Ginkel, Robert J.
AU - Hoekstra, Harald J.
AU - Eggermont, Alex M.M.
AU - Pras, Elisabeth
AU - Koops, Heimen Schraffordt
PY - 1996
Y1 - 1996
N2 - A 57-year-old woman presented with the second recurrence of a high-grade malignant fibrous histiocytoma of the right foot, following previous local resection plus curative adjuvant radiotherapy. The first recurrence of the lesion was treated by isolated limb perfusion with cisplatin; the second recurrence was treated by isolated limb perfusion with tumor necrosis factor, interferon, and melphalan. The tumor and the area that had been irradiated showed a bluish color a few hours after tumor necrosis factor perfusion. Amputation of the right foot and leg below the knee had to be performed because of severe necrosis.
AB - A 57-year-old woman presented with the second recurrence of a high-grade malignant fibrous histiocytoma of the right foot, following previous local resection plus curative adjuvant radiotherapy. The first recurrence of the lesion was treated by isolated limb perfusion with cisplatin; the second recurrence was treated by isolated limb perfusion with tumor necrosis factor, interferon, and melphalan. The tumor and the area that had been irradiated showed a bluish color a few hours after tumor necrosis factor perfusion. Amputation of the right foot and leg below the knee had to be performed because of severe necrosis.
UR - http://www.scopus.com/inward/record.url?scp=0030010921&partnerID=8YFLogxK
U2 - 10.1001/archsurg.1996.01430180098022
DO - 10.1001/archsurg.1996.01430180098022
M3 - Article
C2 - 8645079
AN - SCOPUS:0030010921
SN - 0004-0010
VL - 131
SP - 672
EP - 684
JO - Archives of Surgery
JF - Archives of Surgery
IS - 6
ER -