TY - JOUR
T1 - Kaposiform (spindle cell) hemangioendotelioma in a child with an unusual presentation
AU - Veening, Margreet A.
AU - Verbeke, Jonathan I.
AU - Witbreuk, Melinda M.
AU - Kaspers, Gert Jan L.
PY - 2010/4
Y1 - 2010/4
N2 - We describe a male child with multifocal kaposiform hemangioendothelioma in the right and left cervical region with development of Kasabach-Merritt syndrome. Treatment with interferon-α resulted in a good but only temporary clinical response. He relapsed 3 times with regrowth of the right cervical tumor. Involvement of the liver is suspected, because normalization of the liver size followed after the treatment with interferon-α. The question remains whether the multiple osteolytic bone lesions also reflect kaposiform hemangioendothelioma localization.
AB - We describe a male child with multifocal kaposiform hemangioendothelioma in the right and left cervical region with development of Kasabach-Merritt syndrome. Treatment with interferon-α resulted in a good but only temporary clinical response. He relapsed 3 times with regrowth of the right cervical tumor. Involvement of the liver is suspected, because normalization of the liver size followed after the treatment with interferon-α. The question remains whether the multiple osteolytic bone lesions also reflect kaposiform hemangioendothelioma localization.
KW - Hemostasis
KW - Pediatric hematology/oncology
KW - Rare tumors
UR - http://www.scopus.com/inward/record.url?scp=77951030168&partnerID=8YFLogxK
U2 - 10.1097/MPH.0b013e3181ced284
DO - 10.1097/MPH.0b013e3181ced284
M3 - Article
C2 - 20387265
AN - SCOPUS:77951030168
SN - 1077-4114
VL - 32
SP - 240
EP - 242
JO - Journal of Pediatric Hematology/Oncology
JF - Journal of Pediatric Hematology/Oncology
IS - 3
ER -