Samenvatting
We karyotyped a metastasis composed of pure yolk sac tumor derived from a primary ovarian germ cell tumor with two components: a dermoid cyst [DNA index (DI) 1.0] and a pure yolk sac tumor (DI 1.88). The metastatic yolk sac tumor had a hypertriploid karyotype and a DI of 1.78 and lacked the germ cell tumor marker i(12p). The absence of this marker in a metastasis from a tumor with a dermoid cyst component might be indicative for a pathogenesis of the yolk sac tumor similar to that of a dermoid cyst and different from that of dysgerminoma.
Originele taal-2 | Engels |
---|---|
Pagina's (van-tot) | 223-228 |
Aantal pagina's | 6 |
Tijdschrift | Cancer Genetics and Cytogenetics |
Volume | 44 |
Nummer van het tijdschrift | 2 |
DOI's | |
Status | Gepubliceerd - feb. 1990 |
Extern gepubliceerd | Ja |