Karyotyping and DNA flow cytometry of metastatic ovarian yolk sac tumor

Anne Marie Vos; J. Wolter Oosterhuis; Bauke de Jong; Sérgio M.M.J. Castedo; Harry Hollema; Janneke Buist; Jan G. Aalders

doi:10.1016/0165-4608(90)90051-B

Karyotyping and DNA flow cytometry of metastatic ovarian yolk sac tumor

Anne Marie Vos, J. Wolter Oosterhuis, Bauke de Jong, Sérgio M.M.J. Castedo, Harry Hollema, Janneke Buist, Jan G. Aalders

Onderzoeksoutput: Bijdrage aan tijdschrift › Artikel › peer review

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We karyotyped a metastasis composed of pure yolk sac tumor derived from a primary ovarian germ cell tumor with two components: a dermoid cyst [DNA index (DI) 1.0] and a pure yolk sac tumor (DI 1.88). The metastatic yolk sac tumor had a hypertriploid karyotype and a DI of 1.78 and lacked the germ cell tumor marker i(12p). The absence of this marker in a metastasis from a tumor with a dermoid cyst component might be indicative for a pathogenesis of the yolk sac tumor similar to that of a dermoid cyst and different from that of dysgerminoma.

Originele taal-2	Engels
Pagina's (van-tot)	223-228
Aantal pagina's	6
Tijdschrift	Cancer Genetics and Cytogenetics
Volume	44
Nummer van het tijdschrift	2
DOI's	https://doi.org/10.1016/0165-4608(90)90051-B
Status	Gepubliceerd - feb. 1990
Extern gepubliceerd	Ja

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title = "Karyotyping and DNA flow cytometry of metastatic ovarian yolk sac tumor",

abstract = "We karyotyped a metastasis composed of pure yolk sac tumor derived from a primary ovarian germ cell tumor with two components: a dermoid cyst [DNA index (DI) 1.0] and a pure yolk sac tumor (DI 1.88). The metastatic yolk sac tumor had a hypertriploid karyotype and a DI of 1.78 and lacked the germ cell tumor marker i(12p). The absence of this marker in a metastasis from a tumor with a dermoid cyst component might be indicative for a pathogenesis of the yolk sac tumor similar to that of a dermoid cyst and different from that of dysgerminoma.",

author = "Vos, \{Anne Marie\} and Oosterhuis, \{J. Wolter\} and \{de Jong\}, Bauke and Castedo, \{S{\'e}rgio M.M.J.\} and Harry Hollema and Janneke Buist and Aalders, \{Jan G.\}",

year = "1990",

month = feb,

doi = "10.1016/0165-4608(90)90051-B",

language = "English",

volume = "44",

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T1 - Karyotyping and DNA flow cytometry of metastatic ovarian yolk sac tumor

AU - Vos, Anne Marie

AU - Oosterhuis, J. Wolter

AU - de Jong, Bauke

AU - Castedo, Sérgio M.M.J.

AU - Hollema, Harry

AU - Buist, Janneke

AU - Aalders, Jan G.

PY - 1990/2

Y1 - 1990/2

N2 - We karyotyped a metastasis composed of pure yolk sac tumor derived from a primary ovarian germ cell tumor with two components: a dermoid cyst [DNA index (DI) 1.0] and a pure yolk sac tumor (DI 1.88). The metastatic yolk sac tumor had a hypertriploid karyotype and a DI of 1.78 and lacked the germ cell tumor marker i(12p). The absence of this marker in a metastasis from a tumor with a dermoid cyst component might be indicative for a pathogenesis of the yolk sac tumor similar to that of a dermoid cyst and different from that of dysgerminoma.

AB - We karyotyped a metastasis composed of pure yolk sac tumor derived from a primary ovarian germ cell tumor with two components: a dermoid cyst [DNA index (DI) 1.0] and a pure yolk sac tumor (DI 1.88). The metastatic yolk sac tumor had a hypertriploid karyotype and a DI of 1.78 and lacked the germ cell tumor marker i(12p). The absence of this marker in a metastasis from a tumor with a dermoid cyst component might be indicative for a pathogenesis of the yolk sac tumor similar to that of a dermoid cyst and different from that of dysgerminoma.

UR - https://www.scopus.com/pages/publications/0025124450

U2 - 10.1016/0165-4608(90)90051-B

DO - 10.1016/0165-4608(90)90051-B

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AN - SCOPUS:0025124450

SN - 0165-4608

VL - 44

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EP - 228

JO - Cancer Genetics and Cytogenetics

JF - Cancer Genetics and Cytogenetics

IS - 2

ER -

Karyotyping and DNA flow cytometry of metastatic ovarian yolk sac tumor

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