Loss of the Tumor Suppressor CYLD Enhances Wnt/β-Catenin Signaling through K63-Linked Ubiquitination of Dvl

Keyphrases

• Tumor Suppressor 100%
• Beta-catenin 100%
• Cylindromatosis 100%
• K63-linked Ubiquitination 100%
• Wnt/-catenin Signaling 100%
• Tumor Growth 50%
• Ubiquitination 50%
• Tumor Suppressor Gene 50%
• Wnt Signaling 50%
• Gene Transcription 50%
• Frizzled Receptors 50%
• Plasma Membrane 50%
• Wnt Receptors 50%
• Negative Regulator 50%
• Receptor-mediated 50%
• Signaling Activity 50%
• Cultured Cells 50%
• Deubiquitinating Enzyme 50%
• Polymerized 50%
• Gene Activation 50%
• Cylindroma 50%
• Membrane Recruitment 50%
• Membrane Activation 50%
• Cytoplasmic Effectors 50%
• Skin Tumor 50%
• DIX Domain 50%

Biochemistry, Genetics and Molecular Biology

• Ubiquitination 100%
• Tumor Suppressor Protein 100%
• Catenin 100%
• Dishevelled 100%
• Tumor Progression 20%
• Tumor Suppressor Gene 20%
• Wnt Signaling Pathway 20%
• Genetic Transcription 20%
• Frizzled 20%
• Cell Membrane 20%
• Deubiquitinating Enzyme 20%
• Gene Activation 20%