TY - GEN
T1 - Microarray image denoising using a two-stage multiresolution technique
AU - Stefanou, Hara
AU - Margaritis, Thanasis
AU - Kafetzopoulos, Dimitris
AU - Marias, Konstantinos
AU - Tsakalides, Panagiotis
PY - 2007
Y1 - 2007
N2 - DNA microarrays have demonstrated an excellent potential in correlating specific gene expression profiles to specific conditions. However, they are affected by inherent noise. This paper presents a two-stage approach for noise removal that processes the additive and the multiplicative noise component. The proposed approach first decomposes the signal by a multiresolution transform and then accounts for both the multiscale correlation of the subband decompositions and their heavy-tailed statistics. Real microarray images have been processed by the proposed method and its improved performance is shown through quantitative measures and qualitative visual evaluation.
AB - DNA microarrays have demonstrated an excellent potential in correlating specific gene expression profiles to specific conditions. However, they are affected by inherent noise. This paper presents a two-stage approach for noise removal that processes the additive and the multiplicative noise component. The proposed approach first decomposes the signal by a multiresolution transform and then accounts for both the multiscale correlation of the subband decompositions and their heavy-tailed statistics. Real microarray images have been processed by the proposed method and its improved performance is shown through quantitative measures and qualitative visual evaluation.
UR - http://www.scopus.com/inward/record.url?scp=49049096679&partnerID=8YFLogxK
U2 - 10.1109/BIBM.2007.32
DO - 10.1109/BIBM.2007.32
M3 - Conference contribution
AN - SCOPUS:49049096679
SN - 0769530311
SN - 9780769530314
T3 - Proceedings - 2007 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2007
SP - 383
EP - 389
BT - Proceedings - 2007 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2007
T2 - 2007 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2007
Y2 - 2 November 2007 through 4 November 2007
ER -