Model-based treatment optimization of a novel VEGFR inhibitor

Keyphrases

• VEGF Inhibitors 100%
• Treatment Optimization 100%
• Lenvatinib 100%
• Model Guided Therapy 100%
• Once-daily 75%
• Intervention Design 75%
• Adverse Events 50%
• Number of Patients 50%
• Dose Escalation 50%
• Hypertension 50%
• Dose Level 50%
• Dose Titration 50%
• Patient Dose 25%
• Treatment Efficacy 25%
• Dosing Strategy 25%
• Blood Pressure 25%
• Phase II Study 25%
• Drug Exposure 25%
• Treatment Outcome 25%
• Twice Daily 25%
• Dropout 25%
• PK-PD Model 25%
• Intervention Strategies 25%
• Daily Regimen 25%
• Mean Dose 25%
• Antihypertension 25%
• Adaptive Treatment 25%
• 25Mg 25%
• E7080 25%
• PKPD Modeling 25%
• Treatment Design 25%
• Antihypertensive Treatment 25%
• VEGF Receptor Inhibitor 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Lenvatinib 100%
• Adverse Event 40%
• Biological Marker 20%
• Combination Therapy 20%
• Vasculotropin Receptor 20%
• PK/PD Models 20%
• Antihypertensive Agent 20%