Samenvatting
Reliable temperature and thermal-dose measurements using proton resonance frequency shift-based magnetic resonance (MR) thermometry for MR-guided ablation of abdominal organs require a robust correction of artefacts induced by the target displacement through an inhomogeneous and time-variant magnetic field. Two correction approaches emerged recently as promising candidates to allow continuous real-time MR-thermometry under free-breathing conditions: The multibaseline correction method, which relies on a pre-recorded correction table allowing to correct for periodic phase changes, and the referenceless method, which depends on a background phase estimation in the target area based on the assumption of a smooth spatial variation of the phase across the organ. This study combines both methods with real-time in-plane motion correction to permit both temperature and thermal-dose calculations on the fly. Subsequently, the practical aspects of both methods are compared in two application scenarios, a radio frequency-ablation and a high-intensity focused ultrasound ablation. A hybrid approach is presented that exploits the strong points of both methods, allowing accurate and precise proton resonance frequency-thermometry measurements during periodical displacement, even in the presence of spontaneous motion and strong susceptibility variations in the target area.
Originele taal-2 | Engels |
---|---|
Pagina's (van-tot) | 1373-1381 |
Aantal pagina's | 9 |
Tijdschrift | Magnetic Resonance in Medicine |
Volume | 64 |
Nummer van het tijdschrift | 5 |
DOI's | |
Status | Gepubliceerd - nov. 2010 |
Extern gepubliceerd | Ja |