Multiclonal complexity of pediatric acute lymphoblastic leukemia and the prognostic relevance of subclonal mutations

Keyphrases

• Pediatric Acute Lymphoblastic Leukemia 100%
• Prognostic Relevance 100%
• Subclonal mutations 100%
• Subclonal 100%
• Acute Lymphoblastic Leukemia 66%
• Clinical Significance 33%
• Subclone 33%
• Associated Genes 33%
• IKZF1 33%
• Genetic Modification 16%
• Working Diagnosis 16%
• Pathway mutation 16%
• Tumor Protein p53 (TP53) 16%
• WHSC1 16%
• Hotspot mutation 16%
• Risk Group Stratification 16%
• Initial Diagnosis 16%
• Prognostic Value 16%
• RAS Pathway 16%
• Clonal Expansion 16%
• Leukemia Therapy 16%
• Genomic Studies 16%
• CREB1 16%
• NT5C2 16%
• Molecular Inversion Probes 16%
• Allele Frequency 16%
• Prognostic Marker 16%
• PTPN11 16%
• Unfavorable Outcome 16%
• Relevance Value 16%

Biochemistry, Genetics and Molecular Biology

• IKZF1 100%
• Genomics 100%
• WHSC1 50%
• Gene Frequency 50%
• KRAS 50%
• High Risk Population 50%
• Molecular Inversion Probe 50%
• PTPN11 50%