Mutations in WNT1 cause different forms of bone fragility

Keyphrases

• Age-related Osteoporosis 12%
• Autosomal Recessive Osteogenesis Imperfecta 12%
• Bone Development 12%
• Bone Fragility 100%
• Bone Mass 12%
• Catenin 12%
• Congenital Disorders 25%
• Consanguineous Family 12%
• Culture in Vitro 12%
• Early-onset Osteoporosis 12%
• Frameshift mutation 12%
• Function Development 12%
• Functional Analysis 12%
• Heterozygous Variant 12%
• Homozygous mutation 12%
• Homozygous Variant 12%
• Low Bone Mass 12%
• Low-density Lipoprotein Receptor-related Protein 5 (LRP5) 12%
• Missense mutation 25%
• Nonsense mutation 12%
• Osteoblast 12%
• Osteoblast Functions 12%
• Recurrent Fracture 12%
• Splicing mutation 12%
• Therapeutic Strategies 12%
• Wnt1 100%

Biochemistry, Genetics and Molecular Biology

• Allele 14%
• Autosomal Recessive Inheritance 14%
• Bone Development 28%
• Bone Mass 28%
• Catenin 14%
• Frameshift Mutation 14%
• LRP5 14%
• Missense Mutation 28%
• Nonsense Mutation 14%
• Osteoblast 28%
• Splice Site Mutation 14%
• WNT1 100%