Neogenin1 is a sonic hedgehog target in medulloblastoma and is necessary for cell cycle progression

Keyphrases

• Cell Cycle Progression 100%
• Medulloblastoma 100%
• Sonic Hedgehog 100%
• Sonic Hedgehog Pathway 83%
• Tumor 16%
• Therapeutic Target 16%
• Loss Function 16%
• Gene Expression Profiling 16%
• Binding Site 16%
• Mouse Model 16%
• Precursor Cells 16%
• Downstream Effectors 16%
• Medulloblastoma Subgroups 16%
• Cerebellar Development 16%
• M Phase 16%
• Central Nervous System Development 16%
• Transcriptional Targets 16%
• Sonic Hedgehog Medulloblastoma 16%
• First Intron 16%
• Neural Precursors 16%
• Granule Neuron Precursors 16%
• Pathway Modulation 16%
• Cerebellar Growth 16%
• Dependence Receptors 16%
• Upstream Sequence 16%
• Hedgehog-Gli 16%

Biochemistry, Genetics and Molecular Biology

• Cell Cycle Progression 100%
• Sonic Hedgehog 100%
• Hedgehog Signaling Pathway 41%
• Precursor 16%
• Promoter Region 8%
• Gene Expression Profiling 8%
• Binding Site 8%
• Intron 8%
• Mouse Model 8%
• Mediator 8%
• Nervous System Development 8%
• Cell Cycle M Phase 8%
• Mitosis 8%
• Dependence Receptor 8%