Neonatal hepatic haemangioendothelioma: treatment options and dilemmas

Bram B van der Meijs, Johannes H M Merks, Timo R de Haan, Merit M Tabbers, Rick R van Rijn

Onderzoeksoutput: Bijdrage aan tijdschriftArtikelpeer review


We describe a case of rapidly progressive neonatal diffuse hepatic haemangioendotheliomas. The clinical picture was characterized by respiratory insufficiency due to gross abdominal enlargement, coagulopathy, and the development of cardiovascular insufficiency during the course of disease. Pharmacological, radiotherapeutic and endovascular treatment options all proved ineffective. We describe our own experience and the steps taken to treat this child. Unfortunately, the child died as a consequence of the disease. As cases like this are rare and are associated with severe morbidity and high mortality, more knowledge needs to be gained on infantile hepatic haemangioendotheliomas and their optimal treatment. The use of a web-based data registry could be beneficial.

Originele taal-2Engels
Pagina's (van-tot)277-81
Aantal pagina's5
TijdschriftPediatric radiology
Nummer van het tijdschrift3
StatusGepubliceerd - dec. 2008
Extern gepubliceerdJa


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