Oncogene-inducible organoids as a miniature platform to assess cancer characteristics

Tomohiro Mizutani; Yoshiyuki Tsukamoto; Hans Clevers

doi:10.1083/jcb.201704014

Oncogene-inducible organoids as a miniature platform to assess cancer characteristics

Tomohiro Mizutani
, Yoshiyuki Tsukamoto
, Hans Clevers

Onderzoeksoutput: Bijdrage aan tijdschrift › Opmerking/debat

2 Citaten (Scopus)

Samenvatting

Direct effects of oncogenic proteins or inhibitor treatments on signaling pathways are difficult to assess in transgenic mice. In this issue, Riemer et al. (2017. J. Cell Biol. https ://doi .org /10 .1083 /jcb .201610058) demonstrate that oncogene-inducible organoids offer the experimental versatility of two-dimensional cell lines, while closely representing the in vivo situation.

Originele taal-2	Engels
Pagina's (van-tot)	1505-1507
Aantal pagina's	3
Tijdschrift	Journal of Cell Biology
Volume	216
Nummer van het tijdschrift	6
DOI's	https://doi.org/10.1083/jcb.201704014
Status	Gepubliceerd - 1 jun. 2017
Extern gepubliceerd	Ja

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title = "Oncogene-inducible organoids as a miniature platform to assess cancer characteristics",

abstract = "Direct effects of oncogenic proteins or inhibitor treatments on signaling pathways are difficult to assess in transgenic mice. In this issue, Riemer et al. (2017. J. Cell Biol. https ://doi .org /10 .1083 /jcb .201610058) demonstrate that oncogene-inducible organoids offer the experimental versatility of two-dimensional cell lines, while closely representing the in vivo situation.",

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AU - Clevers, Hans

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Oncogene-inducible organoids as a miniature platform to assess cancer characteristics

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