Oncogenic activation of FOXR1 by 11q23 intrachromosomal deletion-fusions in neuroblastoma

Biochemistry, Genetics and Molecular Biology

• Carcinogenesis 100%
• Transcription Factors 100%
• Fusion Transcript 100%
• Messenger RNA 100%
• Gene Fusion 50%
• Embryogenesis 50%
• Tumor Suppressor Gene 50%
• Chromosome 11q 50%
• Wild Type 50%
• RNA Interference 50%
• Transgene 50%
• Transcription 50%
• Neural Crest 50%
• Single-Nucleotide Polymorphism 50%
• Fusion Gene 50%
• Comparative Genomic Hybridization 50%
• Haploinsufficiency 50%
• Loss of Heterozygosity 50%
• Stem Cell Line 50%
• Programmed Cell Death 50%
• Bioinformatics 50%

Keyphrases

• Neuroblastoma 100%
• FOXR1 100%
• Oncogenic Activation 100%
• Overexpression 18%
• Microdeletion 18%
• Fusion Transcript 18%
• Tumor 9%
• Gene Fusion 9%
• Fusion Gene 9%
• Transcription Factor 9%
• Tumor Suppressor Gene 9%
• Neuroblastoma Tumor 9%
• Chromosome 11q 9%
• Tumor Subtype 9%
• Apoptosis 9%
• Loss of Heterozygosity 9%
• Fusion Product 9%
• Profile Data 9%
• Negative Regulator 9%
• MRNA Expression 9%
• Expression Profiling 9%
• Haploinsufficiency 9%
• Microarray Analysis 9%
• SNP Array 9%
• Neural Crest Cells 9%
• Affymetrix 9%
• Comparative Genomic Hybridization 9%
• Stem Cell Lines 9%
• Early Embryonic Development 9%
• Bioinformatics Tools 9%
• Affymetrix Microarray 9%
• Reporter Assay 9%
• Forkhead Box 9%
• Osteosarcoma Cell Lines 9%
• Forkhead 9%
• Cell-based Assay 9%
• RNA Silencing 9%
• Interstitial Deletion 9%
• Forkhead Box Transcription Factors 9%
• Headbox 9%
• HOS Cells 9%
• PAFAH1B2 9%