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Overview of the 2022 WHO Classification of Adrenal Cortical Tumors
Ozgur Mete
, Lori A. Erickson
, C. Christofer Juhlin
,
Ronald R. de Krijger
, Hironobu Sasano
, Marco Volante
, Mauro G. Papotti
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peer review
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Keyphrases
WHO Classification
100%
Adrenal Cortical Carcinoma
100%
Mitosis
30%
Tumor
23%
Nodule
23%
Scoring System
23%
Nodular Disease
23%
Macronodule
23%
Tumor Cells
15%
Ki-67
15%
Helsinki
15%
Hyperplasia
15%
New Classification
15%
Angioinvasion
15%
Weiss
15%
Fibrin
15%
Multi-parameter Diagnostics
15%
Cortical Lesions
15%
Aldosterone
15%
Cortical Pathology
15%
Reticulin Algorithm
15%
Pediatric
7%
Malignancy
7%
Oncology
7%
Predictive Biomarker
7%
Bilateral Disease
7%
Metastatic Disease
7%
Immunohistochemistry
7%
Histopathological Features
7%
Morphological Characteristics
7%
Functional Site
7%
Tumor Biology
7%
Genetic Findings
7%
Submillimeter
7%
Molecular Biology
7%
Prognostic Impact
7%
Carcinoma
7%
Tumor Grade
7%
Tumor Proliferation
7%
Adrenal Gland
7%
Microvascular Invasion
7%
Histological Criteria
7%
Adrenal Cortex
7%
Diagnostic Biomarker
7%
Insulin-like Growth Factor 2 (IGF2)
7%
Proliferation Index
7%
Ki-67 Index
7%
Sarcomatoid
7%
Vessel Wall
7%
Micronodular
7%
Unifocal
7%
Oncocytic Variant
7%
Diagnostic Algorithm
7%
Vascular Tumor
7%
Accurate Assessment
7%
Adrenocortical Disease
7%
Static Threshold
7%
Thrombus
7%
Complex Tumor
7%
Primary Aldosteronism
7%
High-grade Carcinoma
7%
Low-grade Carcinoma
7%
Ectopic Tissue
7%
Ancillary
7%
Germline Susceptibility
7%
Possible Sources
7%
CYP11B2
7%
Oncocytic Neoplasm
7%
Adrenal Pseudocyst
7%
Endocrine Pathology
7%
Aldosterone Excess
7%
Myxoid
7%
Diagnostic Scheme
7%
Refined Classification
7%
Mitotic Rate
7%
Platelet Thrombus
7%
New Section
7%
Adrenal Neoplasm
7%
Adrenal Myelolipoma
7%
Dynamic Risk Stratification
7%
Ectopia
7%
Adrenal Cyst
7%
Mitotic Count
7%
Functional Lesion
7%
Diagnostic Impact
7%
Nomenclature Change
7%
Medicine and Dentistry
Neoplasm
100%
Disease
66%
Adrenal Cortex Carcinoma
41%
Diagnosis
33%
Biological Marker
25%
Carcinoma
25%
Scoring System
25%
Aldosterone
25%
Tumor Cell
16%
Cushing Syndrome
16%
Brain Cortex Lesion
16%
Ectopic Tissue
16%
Reticulin
16%
Fibrin Clot
16%
Pediatrics
8%
Cancer
8%
Tumor Progression
8%
Metastatic Carcinoma
8%
Immunohistochemistry
8%
Risk Stratification
8%
Morphology
8%
Tumor Biology
8%
Platelet
8%
Adrenal Adenoma
8%
Adrenal Cortex
8%
Pseudocyst
8%
Sarcomatoid
8%
Oncology Pathology
8%
Mitosis Rate
8%
Aldosterone Synthase
8%
Endocrine Pathology
8%
Grading (Tumors)
8%
Primary Hyperaldosteronism
8%
Myelolipoma
8%
Adrenal Cyst
8%
Germ Cell
8%
Adrenal Gland
8%