Paraneoplastic gastro-intestinal anti-Hu syndrome in neuroblastoma

C. A.M. Drukker, H. A. Heij, L. C.D. Wijnaendts, J. I.M.L. Verbeke, G. J.L. Kaspers

Onderzoeksoutput: Bijdrage aan tijdschriftArtikelpeer review

19 Citaten (Scopus)


The anti-Hu syndrome is a well-known paraneoplastic syndrome and may be rarely seen in patients with neuroblastoma. However, it is relatively unknown that anti-Hu antibodies can cause gastrointestinal signs and symptoms. We report on a child with neuro- blastoma who presented with gastro-intestinal disturbances as a result of the anti-Hu syndrome and summaries two similar case reports reported in literature. Neuroblastoma patients with gastrointestinal disturbances, ranging from constipation to a paralytic ileus, might suffer from the gastro-intestinal anti-Hu syndrome. The causative antibodies can be determined to diagnose or exclude this syndrome, and successful treatment is possible.

Originele taal-2Engels
Pagina's (van-tot)396-398
Aantal pagina's3
TijdschriftPediatric Blood and Cancer
Nummer van het tijdschrift3
StatusGepubliceerd - mrt. 2009
Extern gepubliceerdJa


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