Population pharmacokinetic modeling of factor concentrates in hemophilia: An overview and evaluation of best practice

Keyphrases

• Hemophilia 100%
• Factor Concentrates 100%
• Population Pharmacokinetics (PopPK) 100%
• Population Pharmacokinetic Modeling 100%
• Factor IX Concentrate 75%
• Clinical Data 50%
• Laboratory Data 50%
• Literature Search 25%
• Pediatric Patients 25%
• Pharmacokinetics 25%
• NONMEM 25%
• Data Quality 25%
• Model Validation 25%
• Demographic Categories 25%
• Obese Adults 25%
• Pharmacokinetic Profile 25%
• Patient Data 25%
• Overweight Adults 25%
• Data Documentation 25%
• Product Type 25%
• Detailed Data 25%
• Pharmacokinetic Dosing 25%
• Factor Levels 25%
• Hemophilia B 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Pharmacokinetic Modeling 100%
• Haemophilia A 100%
• Pharmacokinetics 100%
• Blood Clotting Factor 8 42%
• Blood Clotting Factor 9 Concentrate 42%
• Haemophilia B 14%
• Blood Clotting Factor 7 14%
• Obesity 14%