TY - JOUR
T1 - Predictors of mortality
T2 - An international comparison of socio-demographic and health characteristics from six longitudinal studies on aging: The CLESA project
AU - Noale, Marianna
AU - Minicuci, Nadia
AU - Bardage, Carola
AU - Gindin, Jacob
AU - Nikula, Suvi
AU - Pluijm, Saskia
AU - Rodríguez-Laso, Angel
AU - Maggi, Stefania
N1 - Funding Information:
The CLESA Project is supported by EU QoL2000-00664.
Funding Information:
The TamELSA is supported by the Academy of Finland, the Juho Vainio Foundation, the Yrjö Jahnsson Foundation, and the Medical Research Fund of Tampere University Hospital. CALAS was supported by the US National Institute on Aging Grants-R01-5885-03 and R01-5885-06. ILSA was supported by the CNR (National Research Council) and the Italian Department of Health—National Institutes of Health. LASA is supported by The Netherlands Ministry of Health, Welfare and Sports and the Vrije Universiteit. Aging in Leganés is supported by the Spanish Health Research Fund (FIS), the Madrid Regional Research Fund and Private Foundations (La Caixa, BBVA). SATSA is supported by the US National Institute on Aging (AG 04563, 10175) and the Swedish Social Research Council.
PY - 2005/1
Y1 - 2005/1
N2 - Multiple factors contribute to mortality in the elderly, but the extent to which traditional factors contribute independently to mortality in different countries is not known. Our objective is to determine the differential impact of socio-demographic variables, selected diseases, health habits and disability on all-cause mortality, among older people living in five European countries and Israel. From six longitudinal studies on aging (TamELSA-Tampere (Finland), CALAS-Israel, ILSA-Italy, LASA-Netherlands, AL-Leganés (Spain), SATSA-Sweden), a harmonized common database was created in the context of the CLESA Project (Cross-national determinants of quality of life and health services for the elderly). A common five-year follow-up was used. The highest mortality rate was found in Tampere among females (98.7‰) and in Israel among males (108.3‰), whereas the lowest was observed in Leganés for males (72.3‰) and in The Netherlands for females (44.6‰). In multivariate models, some predictors were homogeneously, significantly distributed across the six countries, including older age (HR=1.57) and male sex (HR=1.60) among the socio-demographic variables; smoking status (HR=1.15) and alcohol consumption (HR=0.81) among the health habits variables; presence of heart disease (HR=1.34), diabetes (HR=1.46), cancer (HR=1.93), respiratory disease (HR=1.19), and disability (HR=2.92) among the health status variables. Marital status, education, and drug use did not have homogeneous effects in the six countries. This large international study shows that multiple factors contribute to increased risk of all cause mortality among older people and that most risk factors are similar across countries. Disability, age greater than 80 years, cancer and male sex were identified as the strongest common risk factors of mortality.
AB - Multiple factors contribute to mortality in the elderly, but the extent to which traditional factors contribute independently to mortality in different countries is not known. Our objective is to determine the differential impact of socio-demographic variables, selected diseases, health habits and disability on all-cause mortality, among older people living in five European countries and Israel. From six longitudinal studies on aging (TamELSA-Tampere (Finland), CALAS-Israel, ILSA-Italy, LASA-Netherlands, AL-Leganés (Spain), SATSA-Sweden), a harmonized common database was created in the context of the CLESA Project (Cross-national determinants of quality of life and health services for the elderly). A common five-year follow-up was used. The highest mortality rate was found in Tampere among females (98.7‰) and in Israel among males (108.3‰), whereas the lowest was observed in Leganés for males (72.3‰) and in The Netherlands for females (44.6‰). In multivariate models, some predictors were homogeneously, significantly distributed across the six countries, including older age (HR=1.57) and male sex (HR=1.60) among the socio-demographic variables; smoking status (HR=1.15) and alcohol consumption (HR=0.81) among the health habits variables; presence of heart disease (HR=1.34), diabetes (HR=1.46), cancer (HR=1.93), respiratory disease (HR=1.19), and disability (HR=2.92) among the health status variables. Marital status, education, and drug use did not have homogeneous effects in the six countries. This large international study shows that multiple factors contribute to increased risk of all cause mortality among older people and that most risk factors are similar across countries. Disability, age greater than 80 years, cancer and male sex were identified as the strongest common risk factors of mortality.
KW - Aging
KW - Cross-national comparison
KW - Longitudinal studies
KW - Mortality
UR - http://www.scopus.com/inward/record.url?scp=12344292525&partnerID=8YFLogxK
U2 - 10.1016/j.exger.2004.09.003
DO - 10.1016/j.exger.2004.09.003
M3 - Article
C2 - 15732192
AN - SCOPUS:12344292525
SN - 0531-5565
VL - 40
SP - 89
EP - 99
JO - Experimental Gerontology
JF - Experimental Gerontology
IS - 1-2
ER -