Prostate-sparing cystectomy: Long-term oncological results

Remco R. De Vries, Jakko A. Nieuwenhuijzen, Harm Van Tinteren, Jorg R. Oddens, Otto Visser, Henk G. Van Der Poel, Axel Bex, Willem Meinhardt, Simon Horenblas

Onderzoeksoutput: Bijdrage aan tijdschriftArtikelpeer review

22 Citaten (Scopus)

Samenvatting

Objective To analyse the oncological outcome of prostate-sparing cystectomy (PSC). Patients and Methods Between 1994 and 2006, 63 men were treated with PSC after meeting the inclusion criteria (no tumour at the bladder neck, no prostate cancer). The results were compared with patients who had a standard cystoprostatectomy (SC) during the same study period, after matching for clinical and pathological characteristics. Results The 3- and 5-year disease-specific survival rates were 77% and 66% in the PSC group, and 68% and 64% in the SC group (log-rank, P = 0.6). The local recurrence rate was 7.9% and 16% for the PSC and the SC groups, respectively, and the respective distant recurrence rate was 29% and 33%. Subsequent prostate cancer was detected in 3% in the PSC group. None of these patients died from prostate cancer. In the SC group the final pathology showed that 18% had prostate cancer. Conclusion Local recurrences were not diagnosed more often in the PSC than the SC group. The outcomes of both procedures are comparable with contemporary cystoprostatectomy series. We consider this procedure oncologically safe and offer this to selected patients. However, selection is the key to success, and our results should further be corroborated by the experience of others.

Originele taal-2Engels
Pagina's (van-tot)1239-1243
Aantal pagina's5
TijdschriftBJU International
Volume104
Nummer van het tijdschrift9
DOI's
StatusGepubliceerd - nov. 2009
Extern gepubliceerdJa

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