Rat traps: Filling the toolbox for manipulating the rat genome

Ruben van Boxtel; Edwin Cuppen

doi:10.1186/gb-2010-11-9-217

Rat traps: Filling the toolbox for manipulating the rat genome

Ruben van Boxtel
, Edwin Cuppen

Onderzoeksoutput: Bijdrage aan tijdschrift › Artikel recenseren › peer review

11 Citaten (Scopus)

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The laboratory rat is rapidly gaining momentum as a mammalian genetic model organism. Although traditional forward genetic approaches are well established, recent technological developments have enabled efficient gene targeting and mutant generation. Here we outline the current status, possibilities and application of these techniques in the rat.

Originele taal-2	Engels
Artikelnummer	217
Tijdschrift	Genome biology
Volume	11
Nummer van het tijdschrift	9
DOI's	https://doi.org/10.1186/gb-2010-11-9-217
Status	Gepubliceerd - 29 sep. 2010
Extern gepubliceerd	Ja

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10.1186/gb-2010-11-9-217

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title = "Rat traps: Filling the toolbox for manipulating the rat genome",

abstract = "The laboratory rat is rapidly gaining momentum as a mammalian genetic model organism. Although traditional forward genetic approaches are well established, recent technological developments have enabled efficient gene targeting and mutant generation. Here we outline the current status, possibilities and application of these techniques in the rat.",

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AU - Cuppen, Edwin

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AB - The laboratory rat is rapidly gaining momentum as a mammalian genetic model organism. Although traditional forward genetic approaches are well established, recent technological developments have enabled efficient gene targeting and mutant generation. Here we outline the current status, possibilities and application of these techniques in the rat.

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U2 - 10.1186/gb-2010-11-9-217

DO - 10.1186/gb-2010-11-9-217

M3 - Review article

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AN - SCOPUS:77958199171

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JO - Genome biology

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Rat traps: Filling the toolbox for manipulating the rat genome

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