Recurrent NR3C1 Aberrations at First Diagnosis Relate to Steroid Resistance in Pediatric T-Cell Acute Lymphoblastic Leukemia Patients

Keyphrases

• Pediatric 100%
• Aberrations 100%
• Leukemia Patients 100%
• T-cell Acute Lymphoblastic Leukemia (T-ALL) 100%
• Steroid Resistance 100%
• NR3C1 100%
• First Diagnosis 100%
• Acute Lymphoblastic Leukemia 33%
• Acute Lymphoblastic Leukemia Cells 33%
• Working Diagnosis 16%
• Disease Diagnosis 16%
• Patient Samples 16%
• Missense mutation 16%
• Nonsense mutation 16%
• B-cell Acute Lymphoblastic Leukemia (B-ALL) 16%
• Leukemia Cell Lines 16%
• Induced Apoptosis 16%
• Steroid-induced 16%
• Early Thymic Progenitors 16%
• Steroid Response 16%
• Messenger RNA Expression 16%
• Deletion mutation 16%
• Glucocorticoid Receptor 16%
• Primary Diagnostics 16%
• Disease Relapse 16%
• Functional Modeling 16%

Medicine and Dentistry

• Pediatrics 100%
• Acute Lymphoblastic Leukemia 100%
• Steroid Resistance 100%
• Diagnosis 33%
• Disease 16%
• Programmed Cell Death 16%
• Leukemia Cell 16%
• Leukemia Cell Line 16%
• Glucocorticoid Receptor 16%
• Nonsense Mutation 16%
• Missense Mutation 16%
• Messenger RNA 16%

Biochemistry, Genetics and Molecular Biology

• T Cell 100%
• Nonsense Mutation 33%
• Missense Mutation 33%
• Glucocorticoid Receptor 33%
• Messenger RNA 33%