Reduced purifying selection prevails over positive selection in human copy number variant evolution

Keyphrases

• Copy number Variation 100%
• Positive Selection 100%
• Purifying Selection 100%
• Variation Evolution 100%
• Human Population 33%
• Segmental Duplication 25%
• Genomic Variation 8%
• Susceptibility to Disease 8%
• Chromosomal Rearrangements 8%
• Variant Allele 8%
• Orthologs 8%
• Lethality 8%
• Nucleotide Substitution 8%
• Genic 8%
• G+C Content 8%
• Non-essential Genes 8%
• Copy number Variable Regions 8%
• C-sequence 8%
• Deleterious Substitutions 8%
• Sequence number 8%
• Protein Evolutionary Rates 8%
• Gene Density 8%
• Adaptive Benefit 8%
• C Content 8%
• Hill-Robertson Interference 8%

Biochemistry, Genetics and Molecular Biology

• Low Copy Repeats 100%
• Negative Selection (Natural Selection) 100%
• Copy-Number Variation 66%
• GC-content 66%
• Mouse 33%
• Allele 33%
• Chromosomal Rearrangement 33%
• Orthology 33%
• Evolutionary Rate 33%
• Gene Density 33%