Refining the 10-Year Prediction of Left Ventricular Systolic Dysfunction in Long-Term Survivors of Childhood Cancer

Jan M. Leerink, Helena J.H. van der Pal, Leontien C.M. Kremer, Elizabeth A.M. Feijen, Paola G. Meregalli, Milanthy S. Pourier, Remy Merkx, Louise Bellersen, Elvira C. van Dalen, Jacqueline Loonen, Yigal M. Pinto, Livia Kapusta, Annelies M.C. Mavinkurve-Groothuis, Wouter E.M. Kok

Onderzoeksoutput: Bijdrage aan tijdschriftArtikelpeer review

Samenvatting

Background: In childhood cancer survivors (CCS) at risk for heart failure, echocardiographic surveillance recommendations are currently based on anthracyclines and chest-directed radiotherapy dose. Whether the ejection fraction (EF) measured at an initial surveillance echocardiogram can refine these recommendations is unknown. Objectives: The purpose of this study was to assess the added predictive value of EF at >5 years after cancer diagnosis to anthracyclines and chest-directed radiotherapy dose in CCS, for the development of left ventricular dysfunction with an ejection fraction
Originele taal-2Engels
Pagina's (van-tot)62-72
Aantal pagina's11
TijdschriftJACC: CardioOncology
Volume3
Nummer van het tijdschrift1
DOI's
StatusGepubliceerd - 1 mrt. 2021

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