Relationship between genome and epigenome - challenges and requirements for future research

Geneviève Almouzni; Lucia Altucci; Bruno Amati; Neil Ashley; David Baulcombe; Nathalie Beaujean; Christoph Bock; Erik Bongcam-Rudloff; Jean Bousquet; Sigurd Braun; Brigitte Bressac de Paillerets; Marion Bussemakers; Laura Clarke; Ana Conesa; Xavier Estivill; Alireza Fazeli; Neža Grgurević; Ivo Gut; Bastiaan T. Heijmans; Sylvie Hermouet; Jeanine Houwing-Duistermaat; Ilaria Iacobucci; Janez Ilaš; Raju Kandimalla; Susanne Krauss-Etschmann; Paul Lasko; Sören Lehmann; Anders Lindroth; Gregor Majdič; Eric Marcotte; Giovanni Martinelli; Nadine Martinet; Eric Meyer; Cristina Miceli; Ken Mills; Maria Moreno-Villanueva; Ghislaine Morvan; Dörthe Nickel; Beate Niesler; Mariusz Nowacki; Jacek Nowak; Stephan Ossowski; Mattia Pelizzola; Roland Pochet; Uroš Potočnik; Magdalena Radwanska; Jeroen Raes; Magnus Rattray; Mark D. Robinson; Bernard Roelen; Sascha Sauer; Dieter Schinzer; Eline Slagboom; Tim Spector; Hendrik G. Stunnenberg; Ekaterini Tiligada; Maria Elena Torres-Padilla; Roula Tsonaka; Ann V. Soom; Melita Vidaković; Martin Widschwendter

doi:10.1186/1471-2164-15-487

Relationship between genome and epigenome - challenges and requirements for future research

Geneviève Almouzni, Lucia Altucci, Bruno Amati, Neil Ashley, David Baulcombe, Nathalie Beaujean, Christoph Bock, Erik Bongcam-Rudloff, Jean Bousquet, Sigurd Braun, Brigitte Bressac de Paillerets, Marion Bussemakers, Laura Clarke, Ana Conesa, Xavier Estivill, Alireza Fazeli, Neža Grgurević, Ivo Gut, Bastiaan T. Heijmans, Sylvie HermouetJeanine Houwing-Duistermaat, Ilaria Iacobucci, Janez Ilaš, Raju Kandimalla, Susanne Krauss-Etschmann, Paul Lasko, Sören Lehmann, Anders Lindroth, Gregor Majdič, Eric Marcotte, Giovanni Martinelli, Nadine Martinet, Eric Meyer, Cristina Miceli, Ken Mills, Maria Moreno-Villanueva, Ghislaine Morvan, Dörthe Nickel, Beate Niesler, Mariusz Nowacki, Jacek Nowak, Stephan Ossowski, Mattia Pelizzola, Roland Pochet, Uroš Potočnik, Magdalena Radwanska, Jeroen Raes, Magnus Rattray, Mark D. Robinson, Bernard Roelen, Sascha Sauer, Dieter Schinzer, Eline Slagboom, Tim Spector, Hendrik G. Stunnenberg, Ekaterini Tiligada, Maria Elena Torres-Padilla, Roula Tsonaka, Ann V. Soom, Melita Vidaković, Martin Widschwendter

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Understanding the links between genetic, epigenetic and non-genetic factors throughout the lifespan and across generations and their role in disease susceptibility and disease progression offer entirely new avenues and solutions to major problems in our society. To overcome the numerous challenges, we have come up with nine major conclusions to set the vision for future policies and research agendas at the European level.

Originele taal-2	Engels
Artikelnummer	487
Tijdschrift	BMC Genomics
Volume	15
Nummer van het tijdschrift	1
DOI's	https://doi.org/10.1186/1471-2164-15-487
Status	Gepubliceerd - 18 jun. 2014
Extern gepubliceerd	Ja

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10.1186/1471-2164-15-487

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Almouzni, G., Altucci, L., Amati, B., Ashley, N., Baulcombe, D., Beaujean, N., Bock, C., Bongcam-Rudloff, E., Bousquet, J., Braun, S., Paillerets, B. B. D., Bussemakers, M., Clarke, L., Conesa, A., Estivill, X., Fazeli, A., Grgurević, N., Gut, I., Heijmans, B. T., ... Widschwendter, M. (2014). Relationship between genome and epigenome - challenges and requirements for future research. BMC Genomics, 15(1), Artikel 487. https://doi.org/10.1186/1471-2164-15-487

@article{1b2e25da11aa40a6bb6c961ee179d677,

title = "Relationship between genome and epigenome - challenges and requirements for future research",

abstract = "Understanding the links between genetic, epigenetic and non-genetic factors throughout the lifespan and across generations and their role in disease susceptibility and disease progression offer entirely new avenues and solutions to major problems in our society. To overcome the numerous challenges, we have come up with nine major conclusions to set the vision for future policies and research agendas at the European level.",

keywords = "Environment, Epigenome, Genome, Microbiome",

author = "Genevi{\`e}ve Almouzni and Lucia Altucci and Bruno Amati and Neil Ashley and David Baulcombe and Nathalie Beaujean and Christoph Bock and Erik Bongcam-Rudloff and Jean Bousquet and Sigurd Braun and Paillerets, {Brigitte Bressac de} and Marion Bussemakers and Laura Clarke and Ana Conesa and Xavier Estivill and Alireza Fazeli and Ne{\v z}a Grgurevi{\'c} and Ivo Gut and Heijmans, {Bastiaan T.} and Sylvie Hermouet and Jeanine Houwing-Duistermaat and Ilaria Iacobucci and Janez Ila{\v s} and Raju Kandimalla and Susanne Krauss-Etschmann and Paul Lasko and S{\"o}ren Lehmann and Anders Lindroth and Gregor Majdi{\v c} and Eric Marcotte and Giovanni Martinelli and Nadine Martinet and Eric Meyer and Cristina Miceli and Ken Mills and Maria Moreno-Villanueva and Ghislaine Morvan and D{\"o}rthe Nickel and Beate Niesler and Mariusz Nowacki and Jacek Nowak and Stephan Ossowski and Mattia Pelizzola and Roland Pochet and Uro{\v s} Poto{\v c}nik and Magdalena Radwanska and Jeroen Raes and Magnus Rattray and Robinson, {Mark D.} and Bernard Roelen and Sascha Sauer and Dieter Schinzer and Eline Slagboom and Tim Spector and Stunnenberg, {Hendrik G.} and Ekaterini Tiligada and Torres-Padilla, {Maria Elena} and Roula Tsonaka and Soom, {Ann V.} and Melita Vidakovi{\'c} and Martin Widschwendter",

note = "Funding Information: The European Union is currently funding over 300 epigenetics projects (a High Impact Project, Collaborative Projects, Networks of Excellence, ERC (European Research Council) Starting Grants, ERC Advanced Grants, Marie Curie Actions) with a total contribution of more than €200 Million.",

year = "2014",

month = jun,

day = "18",

doi = "10.1186/1471-2164-15-487",

language = "English",

volume = "15",

journal = "BMC Genomics",

issn = "1471-2164",

publisher = "BioMed Central Ltd.",

number = "1",

}

Almouzni, G, Altucci, L, Amati, B, Ashley, N, Baulcombe, D, Beaujean, N, Bock, C, Bongcam-Rudloff, E, Bousquet, J, Braun, S, Paillerets, BBD, Bussemakers, M, Clarke, L, Conesa, A, Estivill, X, Fazeli, A, Grgurević, N, Gut, I, Heijmans, BT, Hermouet, S, Houwing-Duistermaat, J, Iacobucci, I, Ilaš, J, Kandimalla, R, Krauss-Etschmann, S, Lasko, P, Lehmann, S, Lindroth, A, Majdič, G, Marcotte, E, Martinelli, G, Martinet, N, Meyer, E, Miceli, C, Mills, K, Moreno-Villanueva, M, Morvan, G, Nickel, D, Niesler, B, Nowacki, M, Nowak, J, Ossowski, S, Pelizzola, M, Pochet, R, Potočnik, U, Radwanska, M, Raes, J, Rattray, M, Robinson, MD, Roelen, B, Sauer, S, Schinzer, D, Slagboom, E, Spector, T, Stunnenberg, HG, Tiligada, E, Torres-Padilla, ME, Tsonaka, R, Soom, AV, Vidaković, M & Widschwendter, M 2014, 'Relationship between genome and epigenome - challenges and requirements for future research', BMC Genomics, vol. 15, nr. 1, 487. https://doi.org/10.1186/1471-2164-15-487

TY - JOUR

T1 - Relationship between genome and epigenome - challenges and requirements for future research

AU - Almouzni, Geneviève

AU - Altucci, Lucia

AU - Amati, Bruno

AU - Ashley, Neil

AU - Baulcombe, David

AU - Beaujean, Nathalie

AU - Bock, Christoph

AU - Bongcam-Rudloff, Erik

AU - Bousquet, Jean

AU - Braun, Sigurd

AU - Paillerets, Brigitte Bressac de

AU - Bussemakers, Marion

AU - Clarke, Laura

AU - Conesa, Ana

AU - Estivill, Xavier

AU - Fazeli, Alireza

AU - Grgurević, Neža

AU - Gut, Ivo

AU - Heijmans, Bastiaan T.

AU - Hermouet, Sylvie

AU - Houwing-Duistermaat, Jeanine

AU - Iacobucci, Ilaria

AU - Ilaš, Janez

AU - Kandimalla, Raju

AU - Krauss-Etschmann, Susanne

AU - Lasko, Paul

AU - Lehmann, Sören

AU - Lindroth, Anders

AU - Majdič, Gregor

AU - Marcotte, Eric

AU - Martinelli, Giovanni

AU - Martinet, Nadine

AU - Meyer, Eric

AU - Miceli, Cristina

AU - Mills, Ken

AU - Moreno-Villanueva, Maria

AU - Morvan, Ghislaine

AU - Nickel, Dörthe

AU - Niesler, Beate

AU - Nowacki, Mariusz

AU - Nowak, Jacek

AU - Ossowski, Stephan

AU - Pelizzola, Mattia

AU - Pochet, Roland

AU - Potočnik, Uroš

AU - Radwanska, Magdalena

AU - Raes, Jeroen

AU - Rattray, Magnus

AU - Robinson, Mark D.

AU - Roelen, Bernard

AU - Sauer, Sascha

AU - Schinzer, Dieter

AU - Slagboom, Eline

AU - Spector, Tim

AU - Stunnenberg, Hendrik G.

AU - Tiligada, Ekaterini

AU - Torres-Padilla, Maria Elena

AU - Tsonaka, Roula

AU - Soom, Ann V.

AU - Vidaković, Melita

AU - Widschwendter, Martin

N1 - Funding Information: The European Union is currently funding over 300 epigenetics projects (a High Impact Project, Collaborative Projects, Networks of Excellence, ERC (European Research Council) Starting Grants, ERC Advanced Grants, Marie Curie Actions) with a total contribution of more than €200 Million.

PY - 2014/6/18

Y1 - 2014/6/18

N2 - Understanding the links between genetic, epigenetic and non-genetic factors throughout the lifespan and across generations and their role in disease susceptibility and disease progression offer entirely new avenues and solutions to major problems in our society. To overcome the numerous challenges, we have come up with nine major conclusions to set the vision for future policies and research agendas at the European level.

AB - Understanding the links between genetic, epigenetic and non-genetic factors throughout the lifespan and across generations and their role in disease susceptibility and disease progression offer entirely new avenues and solutions to major problems in our society. To overcome the numerous challenges, we have come up with nine major conclusions to set the vision for future policies and research agendas at the European level.

KW - Environment

KW - Epigenome

KW - Genome

KW - Microbiome

UR - http://www.scopus.com/inward/record.url?scp=84902300179&partnerID=8YFLogxK

U2 - 10.1186/1471-2164-15-487

DO - 10.1186/1471-2164-15-487

M3 - Article

C2 - 24942464

AN - SCOPUS:84902300179

SN - 1471-2164

VL - 15

JO - BMC Genomics

JF - BMC Genomics

IS - 1

M1 - 487

ER -

Relationship between genome and epigenome - challenges and requirements for future research

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