Silencing of SPRY1 triggers complete regression of rhabdomyosarcoma tumors carrying a mutated RAS gene

Keyphrases

• Tumor 100%
• Rhabdomyosarcoma 100%
• Sprouty1 100%
• Complete Regression 100%
• RAS Genes 100%
• Embryonal Rhabdomyosarcoma 55%
• Extracellular Signal-regulated Kinase 33%
• Childhood Brain Tumors 11%
• Overexpression 11%
• Effective Strategies 11%
• Human Cancer 11%
• RAS Pathway 11%
• Cell Proliferation 11%
• Cell Survival 11%
• Tumorigenicity 11%
• Oncogenic Ras 11%
• Therapeutic Strategies 11%
• Xenograft 11%
• Significantly mutated Genes 11%
• Childhood Rhabdomyosarcoma 11%
• Mitogen-activated Protein 11%
• RAS Status 11%
• Negative Feedback Loop 11%
• RAS Oncogene 11%
• Therapeutic Inhibitors 11%
• RAS mutation 11%
• Tumor Suppressor Function 11%

Biochemistry, Genetics and Molecular Biology

• Kinase 100%
• Phosphotransferase 100%
• Carcinogenesis 25%
• Tumor Suppressor Protein 25%
• Cell Proliferation 25%
• Oncogene 25%
• Cell Survival 25%
• Agonist 25%
• Mutated Genes 25%