Strategies for epigenome analysis

A. B. Brinkman, H. G. Stunnenberg

Onderzoeksoutput: Hoofdstuk in Boek/Rapport/CongresprocedureHoofdstukpeer review

7 Citaten (Scopus)


The eukaryotic genome is packaged into nucleosomes, which form the basal unit of chromatin, the physiological form of DNA within the nucleus. Apart from its function in compacting the immense nuclear DNA molecules, chromatin also serves as a platform onto which multiple signalling pathways converge to cooperate in determining the expression status of mRNAs and other (non-coding) RNA molecules. Epigenetic profile analysis aims to determine what changes on the nucleosomes cooperate to establish and maintain DNA sequence-independent heritable traits such as those determining cell identity.

Originele taal-2Engels
UitgeverijSpringer Netherlands
Aantal pagina's16
ISBN van elektronische versie9781402091872
ISBN van geprinte versie9781402091865
StatusGepubliceerd - 2009
Extern gepubliceerdJa


Duik in de onderzoeksthema's van 'Strategies for epigenome analysis'. Samen vormen ze een unieke vingerafdruk.

Citeer dit