Systematic biases in DNA copy number originate from isolation procedures

Keyphrases

• Array Comparative Genomic Hybridization (aCGH) 50%
• Chromatin 50%
• Chromatin Organization 50%
• Copy number Analysis 100%
• Coverage Bias 50%
• Detection Method 50%
• Detection Signal 50%
• DNA Copy number 100%
• DNA Isolation 50%
• DNA Retrieval 50%
• GC Content 50%
• Gene Copy number Variation 100%
• Gene Expression 50%
• Germ Cells 50%
• Isochores 50%
• Isolation Method 100%
• Main Determinants 50%
• Next-generation Sequencing 50%
• Replication Timing 50%
• Systematic Bias 100%

Biochemistry, Genetics and Molecular Biology

• Array Comparative Genomic Hybridization 50%
• Copy Number Analysis 50%
• Copy-Number Variation 100%
• DNA Isolation 50%
• GC-content 50%
• Gene Dosage 100%
• Gene Expression 50%
• Genomics 50%
• Germ Cell 50%
• Germline 50%
• Information Retrieval 50%
• Isochore 50%
• Isolation Procedure 100%
• Next Generation Sequencing 50%
• Replication Timing 50%
• Signal Detection 50%