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Targeting acute myeloid leukemia by drug-induced c-MYB degradation
V. Walf-Vorderwülbecke
, K. Pearce
, T. Brooks
, M. Hubank
,
M. M. Van Den Heuvel-Eibrink
,
C. M. Zwaan
, S. Adams
, D. Edwards
, J. Bartram
, S. Samarasinghe
, P. Ancliff
, A. Khwaja
, N. Goulden
, G. Williams
, J. De Boer
, O. Williams
Group van den Heuvel
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peer review
90
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Keyphrases
Acute Myeloid Leukemia
100%
Drug-induced
100%
Mebendazole
100%
C-Myb
100%
Novel Therapeutics
33%
Mixed-phenotype Acute Leukemia
33%
Chemotherapy
16%
Fusion Gene
16%
Transcription Factor
16%
Cord Blood
16%
Targeted Drugs
16%
Oncogene
16%
Xenotransplantation
16%
Gene Signature
16%
Leukemia Progression
16%
Colony Formation
16%
Pediatric Leukemia
16%
Acute Myeloid Leukemia Cells
16%
Leukemia Patients
16%
Effective Therapy
16%
Adult Acute Lymphoblastic Leukemia
16%
Heat Shock Protein 70 (HSP70)
16%
Human Use
16%
Chaperone System
16%
MYB Gene
16%
Connectivity Map Database
16%
Medicine and Dentistry
Acute Myeloid Leukemia
100%
Mebendazole
75%
Leukemia
25%
Pediatrics
12%
Disease
12%
Fusion Gene
12%
Transcription Factors
12%
Cord Blood
12%
Oncogene
12%
Gene Expression Profiling
12%
Colony Formation
12%
Drug Delivery System
12%
Leukemia Cell
12%
Xenotransplantation
12%
Proteasome
12%
Heat Shock Protein 70
12%
Chemotherapy
12%
Pharmacology, Toxicology and Pharmaceutical Science
Acute Myeloid Leukemia
100%
Mebendazole
75%
Leukemia
25%
Disease
12%
Chemotherapy
12%
Transcription Factors
12%
Drug Delivery System
12%
Proteasome
12%
Heat Shock Protein 70
12%
Immunology and Microbiology
Myeloid
100%
Lineages
25%
Transcription Factors
12%
Xenotransplantation
12%
Leukemia Cell
12%
Fusion Gene
12%
Heat Shock
12%
Proteasome
12%
Colony Formation
12%
Drug Targeting
12%
Gene Expression Assay
12%
Oncogene
12%
Neuroscience
Mebendazole
75%