The chemosensitizer cyclosporin A enhances the toxic side-effects of doxorubicin in the rat

Keyphrases

• Doxorubicin 100%
• Toxic Side Effects 100%
• Cyclosporine 100%
• Chemosensitizer 100%
• Combination Treatment 57%
• P-glycoprotein (P-gp) 28%
• Enhanced Toxicity 28%
• Cardiomyopathy 14%
• High-level Expression 14%
• Hepatotoxicity 14%
• Kidney 14%
• Expression Level 14%
• Anticancer Drugs 14%
• Dose Effect 14%
• Liver 14%
• Weight Loss 14%
• High Dose 14%
• Adrenal Gland 14%
• Doxorubicin Treatments 14%
• Multidrug Resistance 14%
• Histological Examination 14%
• Leukopenia 14%
• Myelosuppression 14%
• Low Toxicity 14%
• Toxicity Profile 14%
• Pleural Effusion 14%
• Thrombopenia 14%
• Chemosensitizing Effect 14%
• Bilirubin 14%
• Toxicity Characteristic 14%
• Hypertriglyceridemia 14%
• Ascites 14%
• Therapeutic Gain 14%
• Solid Tumor Model 14%
• Nephrotic Syndrome 14%
• Nephrotoxicity 14%
• Hypercholesterolemia 14%
• Large Intestine 14%

Medicine and Dentistry

• Doxorubicin 100%
• Side Effect 100%
• Cyclosporine 100%
• Chemosensitizer 100%
• ABC Transporter Subfamily B 28%
• Solid Malignant Neoplasm 14%
• Liver Toxicity 14%
• Tumor Model 14%
• Drug Megadose 14%
• Anticarcinogen 14%
• Thrombocytopenia 14%
• Leukopenia 14%
• Bone Marrow Suppression 14%
• Multidrug Resistance 14%
• Pleura Effusion 14%
• Hypertriglyceridemia 14%
• Ascites 14%
• Bilirubin 14%
• Nephrotic Syndrome 14%
• Large Intestine 14%
• Hypercholesterolemia 14%
• Nephrotoxicity 14%
• Myocardial Disease 14%
• Adrenal Gland 14%

Pharmacology, Toxicology and Pharmaceutical Science

• Doxorubicin 100%
• Side Effect 100%
• Ciclosporin 100%
• P-Glycoprotein 28%
• Solid Malignant Neoplasm 14%
• Anticarcinogen 14%
• Tumor Model 14%
• Hepatotoxicity 14%
• Thrombocytopenia 14%
• Leukopenia 14%
• Pleura Effusion 14%
• Bone Marrow Suppression 14%
• Hypertriglyceridemia 14%
• Nephrotoxicity 14%
• Nephrotic Syndrome 14%
• Hypercholesterolemia 14%
• Bilirubin 14%
• Ascites 14%
• Myocardial Disease 14%
• Multidrug Resistance 14%