The duration of anthracycline infusion should be at least one hour in children with cancer: A clinical practice guideline

Anthracycline Cardiotoxicity Working Group

Onderzoeksoutput: Bijdrage aan tijdschriftArtikel recenserenpeer review

Samenvatting

We aimed to provide recommendations on the infusion duration of anthracycline chemotherapy agents in children with cancer. This study also serves as a practice example of the essential steps that need to be taken when using a previously published systematic review to develop a high-quality clinical practice guideline. Although evidence was scarce and included adult studies, the panel was able (using the Grading of Recommendations Assessment, Development and Evaluation evidence-to-decision framework) to recommend in favor of an anthracycline infusion duration of at least 1 hr (strong recommendation, very low to moderate quality of evidence). Recommending a precise optimal prolonged infusion duration was currently not possible.

Originele taal-2Engels
TijdschriftPediatric blood & cancer
Volume65
Nummer van het tijdschrift2
DOI's
StatusGepubliceerd - feb. 2018
Extern gepubliceerdJa

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