The role of radiology in paediatric soft tissue sarcomas

K. Park, R. van Rijn, K. McHugh

Onderzoeksoutput: Bijdrage aan tijdschriftArtikel recenserenpeer review

28 Citaten (Scopus)


Paediatric soft tissue sarcomas (STS) are a group of malignant tumours that originate from primitive mesenchymal tissue and account for 7% of all childhood tumours. Rhabdomyosarcomas (RMS) and undifferentiated sarcomas account for approximately 50% of soft tissue sarcomas in children and non-rhabdomyomatous soft tissue sarcomas (NRSTS) the remainder. The prognosis and biology of STS tumours vary greatly depending on the age of the patient, the primary site, tumour size, tumour invasiveness, histologic grade, depth of invasion, and extent of disease at diagnosis. Over recent years, there has been a marked improvement in survival rates in children and adolescents with soft tissue sarcoma and ongoing international studies continue to aim to improve these survival rates whilst attempting to reduce the morbidity associated with treatment. Radiology plays a crucial role in the initial diagnosis and staging of STS, in the long term follow-up and in the assessment of many treatment related complications. We review the epidemiology, histology, clinical presentation, staging and prognosis of soft tissue sarcomas and discuss the role of radiology in their management.

Originele taal-2Engels
Pagina's (van-tot)102-115
Aantal pagina's14
TijdschriftCancer Imaging
Nummer van het tijdschrift1
StatusGepubliceerd - 17 mrt. 2008
Extern gepubliceerdJa


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