The short- and long-term effect of single high-dose intra-operative electron beam irradiation of retroperitoneal structures - An experimental study in dogs

H. J. Hoekstra, D. M. Mehta, J. W. Oosterhuis, P. Westra, J. Van den Dungen, R. G. Dijkstra

Onderzoeksoutput: Bijdrage aan tijdschriftArtikelpeer review

13 Citaten (Scopus)

Samenvatting

Intra-operative electron beam radiotherapy is a new treatment modality. The abdomen is the area of greatest potential applicability of IORT and therefore its effect on retroperitoneal structures was investigated in a canine model. The retroperitoneal structures tolerate 30 to 40 Gy well, with the exception of the radiation-sensitive ureter which showed fibrosis. Twenty to 25 Gy is within the safe dose limits for the clinical application of IORT.

Originele taal-2Engels
Pagina's (van-tot)240-247
Aantal pagina's8
TijdschriftEuropean Journal of Surgical Oncology
Volume16
Nummer van het tijdschrift3
StatusGepubliceerd - 1990
Extern gepubliceerdJa

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