Samenvatting
During neoplastic transformation, cells can promote their own growth by activating proto-oncogenes. Reporting in Cell, Iliopoulos et al. (2009) now show that in certain cell types, a transient oncogenic signal is sufficient to induce neoplastic transformation and to maintain it through a positive feedback loop driven by the inflammatory cytokine interleukin-6.
Originele taal-2 | Engels |
---|---|
Pagina's (van-tot) | 654-6 |
Aantal pagina's | 3 |
Tijdschrift | Cell |
Volume | 139 |
Nummer van het tijdschrift | 4 |
DOI's | |
Status | Gepubliceerd - 13 nov. 2009 |
Extern gepubliceerd | Ja |