Use and application of 3D-organoid technology

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130 Citaten (Scopus)


The capacity of the 3D-organoid cultures to resemble a near-physiological tissue organization and to mimic - to a certain degree - organ functionality, make organoids an excellent model for applications spanning from basic developmental/stem cell research to personalized medicine. Here, we review key findings achieved through organoid technology, and we discuss applications such as disease - and tumour modelling, correction of genetic mutations and understanding gene - and cell functions. Finally, we discuss future developments in the field.

Originele taal-2Engels
Pagina's (van-tot)R99-R107
TijdschriftHuman molecular genetics
Nummer van het tijdschriftR2
StatusGepubliceerd - 1 aug. 2018
Extern gepubliceerdJa


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