Value of neuron specific enolase in early detection of relapse in small cell lung carcinoma

Nico Van Zandwijk; Ewa Jassem; Johannes M.G. Bonfrer; Harm Van Tinteren

doi:10.1016/0277-5379(90)90236-M

Value of neuron specific enolase in early detection of relapse in small cell lung carcinoma

Nico Van Zandwijk, Ewa Jassem, Johannes M.G. Bonfrer, Harm Van Tinteren

Onderzoeksoutput: Bijdrage aan tijdschrift › Artikel › peer review

18 Citaten (Scopus)

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Serum levels of NSE were monitored in 20 SCLC patients who completely responded to combination chemotherapy. An elevation of NSE was observed in five of nine patients with recurrent disease, but predated a relapse in only one. No elevation in NSE level was noted in nine patients who remained in complete remission. The addition of serial assays of LDH to NSE monitoring did not result in any gain in early warning of relapse. This study suggests that the value of serial NSE measurements for predicting a relapse of disease is limited.

Originele taal-2	Engels
Pagina's (van-tot)	373-376
Aantal pagina's	4
Tijdschrift	European Journal of Cancer and Clinical Oncology
Volume	26
Nummer van het tijdschrift	3
DOI's	https://doi.org/10.1016/0277-5379(90)90236-M
Status	Gepubliceerd - mrt. 1990
Extern gepubliceerd	Ja

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title = "Value of neuron specific enolase in early detection of relapse in small cell lung carcinoma",

abstract = "Serum levels of NSE were monitored in 20 SCLC patients who completely responded to combination chemotherapy. An elevation of NSE was observed in five of nine patients with recurrent disease, but predated a relapse in only one. No elevation in NSE level was noted in nine patients who remained in complete remission. The addition of serial assays of LDH to NSE monitoring did not result in any gain in early warning of relapse. This study suggests that the value of serial NSE measurements for predicting a relapse of disease is limited.",

author = "{Van Zandwijk}, Nico and Ewa Jassem and Bonfrer, {Johannes M.G.} and {Van Tinteren}, Harm",

year = "1990",

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AU - Van Zandwijk, Nico

AU - Jassem, Ewa

AU - Bonfrer, Johannes M.G.

AU - Van Tinteren, Harm

PY - 1990/3

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N2 - Serum levels of NSE were monitored in 20 SCLC patients who completely responded to combination chemotherapy. An elevation of NSE was observed in five of nine patients with recurrent disease, but predated a relapse in only one. No elevation in NSE level was noted in nine patients who remained in complete remission. The addition of serial assays of LDH to NSE monitoring did not result in any gain in early warning of relapse. This study suggests that the value of serial NSE measurements for predicting a relapse of disease is limited.

AB - Serum levels of NSE were monitored in 20 SCLC patients who completely responded to combination chemotherapy. An elevation of NSE was observed in five of nine patients with recurrent disease, but predated a relapse in only one. No elevation in NSE level was noted in nine patients who remained in complete remission. The addition of serial assays of LDH to NSE monitoring did not result in any gain in early warning of relapse. This study suggests that the value of serial NSE measurements for predicting a relapse of disease is limited.

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U2 - 10.1016/0277-5379(90)90236-M

DO - 10.1016/0277-5379(90)90236-M

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JF - European Journal of Cancer and Clinical Oncology

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ER -

Value of neuron specific enolase in early detection of relapse in small cell lung carcinoma

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